Dengue fever is a year-round and nationwide risk in Pakistan. While dengue fever is endemic to the coastal areas of Balochistan, activity has historically been highest in Khyber Pakhtunkhwa Province. Authorities reported 3,442 dengue fever cases in Pakistan in 2017, more than 3,200 in 2018, almost 24,547 in 2019, and 3,442 cases in 2020.
Dengue epidemic occured many times in Pakistan including 2011 outbreak, followed by 2017 then 2019.
In October 2019, Prime Minister Imran Khan took notice of the dengue outbreak in the country because it had broken all previous records, and sought report from the Special Assistant to Prime Minister on National Health Services Dr. Zafar Mirza.
On 10 October 2019, a Peshawar High Court bench sent summons to the Khyber Pakhtunkhwa’s provincial health secretary to explain the situation related to dengue outbreak in parts of the province.
Up until October2019, more than 19 000 cases of dengue infection and 30 deaths had been reported by the National Institute of Health, Pakistan, in 2019. From 1995 to 2019, there were around 147 200 cases of dengue infection and over 800 deaths.
Dengue serotype 2 is the most prevalent circulating serotype in Pakistan, with few reported cases of serotype 3. In 2017, the Pakistani northern province of Khyber Pakhtunkhawa faced an epidemic of dengue, with 18 856 cases and multiple deaths, which was attributed to a different lineage of dengue virus serotype 2 circulating in Pakistan. This lineage entered Pakistan from China around 2016 and spread in 2017.